α-АМИНОНИТРИЛЛАР АСОСИДА ГЕТЕРОЦИКЛИК БИРИКМАЛАР СИНТЕЗИ
Keywords:
α-aminonitriles, catalysts, cyanation reactionsAbstract
The article provides preliminary information on the use of α-aminonitriles in organic synthesis, especially in the synthesis of heterocyclic compounds. Catalysts used in their synthesis and their types, as well as information on their effect on the yield of the reaction product, are presented. Also, information on the use of cyanohydrins of various aldehydes as cyanizing reagents is given.
References
Dhanasekaran S., Suneja A., Bisai V., Singh V. K. Org. Lett. -2016. -№18. –Р. 634–637.
Zhang F., Wen X., Xu Q.L., Sun H. Eur. J. Org. Chem. -2014. -№36. –Р.8101–8109.
Hézode C, Forestier N, Dusheiko G, Ferenci P, Pol S, Goeser T, Jean-Pierre Bronowicki J-P, Bourlière M, Gharakhanian S, Bengtsso L, McNair L, George S, Kieffer T, Kwong A, Kauffman RS, Alam J, Pawlotsky J-M, Zeuzem S. New Engl. J. Med. -2009. -№360. –Р. 1839–1850.
Opatz T, Ferenc D. Synthesis. -2008. -№24. –Р. 3941–3944
D. Bartusik, D. Aebischer, P. Tutka. Modern Org. Chem. Res., P.10-23, Vol. 1, №1, 2016.
A. Petruczynik, K. Wróblewski, J. Misiurek, T. Plech, K. Szalast, K. Wojtanowski, T. Mroczek, G. Szymczak, M. Waksmundzka-Hajnos, P. Tutka. Toxins, 2020, 12, 557-576.
P. Tutka, W. Zatoñski. Pharm. Rep., 2006, 58, 777-798.
J. Rouden, M., C. Lasne, J. Blanchet, J. Baudoux. Chem. Rev. 2014, 114, 1, 712–778.
D. Bartusik, D. Aebischer, P. Tutka. Modern Org. Chem. Res., P.10-23, Vol. 1, №1, 2016.
